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” In 1870, during the Franco-Prussian war, Health professionals injected distilled h2o to the dermis To alleviate arthritic pain. In 1885, William Halsted reported that intradermal inoculation of sterile h2o induces local anesthesia. In 1894, Pietro Orlandini, a Venetian health care provider, proposed dermal punctures to the cure of some forms of